Selective neuronal mitochondrial targeting in SARS-CoV-2 infection affects cognitive processes to induce brain fog and results in behavioral changes that favor viral survival. Dis. 10.1136/bjophthalmol-2020-317576. Immunol. The higher frequency of personal history of dry eye or severe symptoms in mild-to-moderate cases needs other studies to be clarified due to a small number of patients in the sample. Breathing exercises and respiratory therapy can help. Angiotensin II and its receptor subtypes in the human retina. V. Brantl and B. Schworm wrote the paper, G. Weber, J. Schiefelbein examined patients, V. Brantl prepared figures and tables, T. Kreutzer, S. Michalakis, J. Siedlecki and S. Priglinger gave final supportive assistance. Long-term ocular damage after recovery from COVID-19: lack of evidence Yes, 2. Two eyes in the hospitalised group were excluded because of epiretinal Membranes. Vinores SA, Wang Y, Vinores MA, Derevjanik NL, Shi A, Klein DA, Detrick B, Hooks JJ. : acquisition of data; analysis and interpretation of data; drafting the manuscript. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. Rep. 8, 2076. https://doi.org/10.1038/s41598-018-20273-9 (2018). This study was approved by the ethics committee of Ludwig-Maximilians-University, Munich, Germany and adhered to the tenets of the Declaration of Helsinki. This study with a small prospective cohort of 21 patients indicates that there might be no evidence of ocular complications at 3months after recovery from COVID-19, without previous eye involvement. Nature. Ocul Immunol Inflamm. For OCT, 3D-Scan mode was used, covering the central 6mm of the macula equalling 320320 pixels. Bethesda, MD 20894, Web Policies In animal experiments (cat, mice), various eye diseases such as uveitis, retinitis and optic neuritis could be triggered by betacoronaviruses indicating an direct uptake into the eye [27]. Further studies with a longer follow-up and a larger sample size are warranted. 28, 12981300 (2020). CAS JAMA 324, 603605. We would like to thank all patients and the study team of our Clinic of Ophthalmology. California Privacy Statement, Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. "We are all seeing very small pieces of the elephant in terms of the long Covid group," Dr. Bell said. The frequency (n=63) of myopia (sph eq<-0.50D) and hyperopia (sph eq>+0.50D) was respectively 31.7% and 41.2% and seems not to be different when compared to prevalence data on refractive errors. Impact of the COVID-19 lockdown on digital device-related ocular health. J. Infect. For the superior, inferior, nasal and temporal quadrants 48.12.1 vs. 46.13.4, 48.22.5 vs. 48.14.9, 46.61.6 vs 44.33.0 and 46.51.7 vs 44.41.3 (Fig. Selective neuronal mitochondrial targeting in SARS-CoV-2 infection affects cognitive processes to induce brain fog and results in behavioral changes that favor viral survival. The most commonly used drugs were azithromycin in 29 (45.3%); heparin in 36 (56.2%); ceftriaxone in 33 (51.5%); and prednisone in 28 (43.7%). Long COVID or Post-COVID Conditions | CDC Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the coronavirus study group. Vis. Look for These Symptoms in the Months After COVID Recovery Lancet 395, 1610. https://doi.org/10.1016/S0140-6736(20)31014-X (2020). https://doi.org/10.1001/jama.2020.12603 (2020). Vavvas DG, Sarraf D, Sadda SR, Eliott D, Ehlers JP, Waheed NK, et al. Article Although in most patients COVID-19 manifests with fever and respiratory tract symptoms, SARS-CoV-2 infection may also involve other organs [37]. Of these, 14 (66.6%) were hospitalized and 7 (33.3) were discharged home. J. Fam. 10.1038/s41433-020-1084-9. This study with a small prospective cohort of 21 patients indicates that there might be no evidence of ocular complications at 3months after recovery from COVID-19, without previous eye involvement. The mean superficial parafoveal vessel density for the central fovea was 21.84.3 for not hospitalized and 21.12.9 for hospitalized patients.