Symptoms of polymorphic light eruption An itchy or burning rash appears within hours, or up to 2 to 3 days after exposure to sunlight. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. [10] It is also thought that skin microbiome or microbial elements could be involved in pathogenesis of the disease [13][14], PLE can be provoked by UVA or UVB (chief cause of sunburn) rays, meaning it can be triggered even by sunlight through glass. Gruber-Wackernagel A, et al. American Academy of Dermatology. PMLE is characterized by recurrent, abnormal, delayed reactions to sunlight, ranging from erythematous papules, papulovesicles, and plaques to erythema multiforme -like . A rash can be a symptom of many different conditions. The .gov means its official. Polymorphous Light Eruption - Medscape Polymorphous light eruption is the most common skin disease resulting from UV light exposure. Doctors think it is a type of delayed allergic reaction. Direct immunofluorescence testing is negative. 1 mo. This hormone may prevent UV radiation from suppressing the skins immune responses. [2], Photoprovocation tests are usually not required but may be undertaken by specialised centres in winter. Polymorphic light eruption pathology Frontiers in medicine. DermNet does not provide an online consultation service. [1] It generally appears 30 minutes to a few hours after sun exposure and may last between one and 14 days. Skin lesions typically appear within hours of sun exposure, but they sometimes occur days later. The rash usually appears as tiny, inflamed bumps or slightly raised patches of skin. Have you had a fever associated with the rash? Last reviewed by a Cleveland Clinic medical professional on 02/20/2023. Br J Dermatol. [4], PLE is more common in young adults and has a female preponderance[5] with a ratio of 2:1 female-to-male. Mayo Clinic. Experts have suggested it may also be at least partly associated with: While the causes of PMLE are still under investigation, the rash is brought on by UV light. Lesions may vary from patient to patient; however, spontaneous resolution (on cessation of sun exposure) is often a unifying trait. Make your tax-deductible gift and be a part of the cutting-edge research and care that's changing medicine. This may explain why females are much more likely to develop PLE than males, as they have more estrogen. A skin biopsy might be taken in order to confirm the diagnosis, but this is not always necessary. If you have a rash in addition to other symptoms that are more serious, you may need emergency care. Willan House, 4 Fitzroy Square, London, W1T 5HQ | admin@bad.org.uk | +44 (0)020 7383 0266 Skin diseases due to physical and chemical causes", https://en.wikipedia.org/w/index.php?title=Polymorphous_light_eruption&oldid=1127125983, Skin conditions resulting from physical factors, Pages containing links to subscription-only content, Creative Commons Attribution-ShareAlike License 3.0, Shortly after sun exposure in people younger than age 30-years, This page was last edited on 13 December 2022, at 01:14. We do not endorse non-Cleveland Clinic products or services. However, this study was small. Polymorphous light eruption is a rash caused by sun exposure in people who have developed sensitivity to sunlight. Majoie IML, van Weelden H, Sybesma IM, Coenraads PJ, Sigurdsson V. Polymorphous light eruption-like skin lesions in welders caused by ultraviolet C light. PMLE affects 10-15% of the US population [], but this number may be higher due to underreporting or patients not seeking medical attention.A Pubmed review reveals, to the best of our knowledge, the first case of a 41-year-old Hispanic female diagnosed with PMLE. Bookshelf All rights reserved. arrow-right-small-blue Polymorphous Light Eruption Differential Diagnoses - Medscape sharing sensitive information, make sure youre on a federal These conditions include: Treatment of polymorphous light eruption usually isn't needed because the rash usually goes away on its own within 10 days. Individual patients tend to develop the same type and pattern of outbreak each year. Reported to be more common at higher altitudes compared to sea level regions. It is primarily caused by either UVA (7590%) or UVB light alone or UVA and UVB light concurrently, UVA can penetrate window glass and some sunscreens do not protect against it. Polymorphous light eruption: clinic aspects and pathogenesis. Epub 2022 Jun 18. A positive family history in some patients suggests a genetic risk factor. Sunscreens containing the broad-spectrum UVA absorber, Mexoryl SX, prevent the cutaneous detrimental effects of UV exposure: a review of clinical study results. Disclaimer. Note that this may not provide an exact translation in all languages, Home Find out if kids need different sunscreens from adults, if sunscreen can be toxic, and whether it matters if youre slathering on SPF 100. Patients with PMLE can develop a tolerance during summer months. In patients with a polymorphic light eruption, Tcell function is not suppressed by UV radiation until photo-hardening has taken place. For polymorphous light eruption, some basic questions to ask your health care provider include: Your health care provider will ask you a number of questions about your symptoms and your medical history, such as: Avoid sun exposure whenever possible. Eruptions appear on sun-exposed areas, usually 30 minutes to several hours after exposure; however . Avoid sunlight, choose shaded areas if outdoors and sit away from windows. Other conditions considered as sun allergies are solar urticaria (hives and reddish patches that usually start 30 minutes to two hours after the sun exposure), actinic . It looks like reddened skin with raised red spots or small blisters. Thus, a patient may benefit from a mental health counsultant. The rash persists for several days then clears up without scarring if further exposure to UV is avoided. If the rash does not go away, a doctor may prescribe topical creams or medications to manage it. This is a type of distinct, circular bump that occurs due to, Erythema multiforme causes a distinctive rash resembling a bull's-eye. It can feel sore or burning. Polymorphous light eruption - Case history | BMJ Best Practice US
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