This one slipped me last year. A Microsoft whitepaper about Instrumentation Best Practices for High Performance BizTalk solutions. A reminder of the impact of trace and debug on BizTalk Developments. It covers Pipeline Components, Maps, Orchestrations, custom .Net components and even Business Rules. An interesting read.
Another interesting link is BizTalk Software Factory 3.0. This new version supports BizTalk Server 2010/Visual Studio 2010, which you can download from Codeplex. Everything that further accelerates BizTalk development is welcome.